Alec jeffreys devised genetic fingerprinting method

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Alec jeffreys

In 1984, Alec Jeffrey, a professor of heredity at the University of Leicester in England, studies the growth of genes. He particularly intrigued by the intron—the series of bases in a genetic material tells to as junk DNA. When the genetic code moved to an opposite mRNA molecule to convert into the proteins, these intron sequences fall out by the special editor.

Introns in DNA Fingerprinting
while analyzing fragments of DNA, Jeffreys see that introns often complete up of the same run of bases repeat again and that the sequences mixed  from one person to the next. Indeed, it is because of variable regions that the DNA from two people never breaks down into the same pattern.
Although Jeffreys had no special worry murder cases at the time. It arises to him that the individual patterns show as a DNA fingerprint. It can become a powerful forensic tool. Biological proof left behind at a crime scene can in step to the person who commits the crime. Blood, semen, saliva and hair-roots—any material has a nucleated cell. It can offer a tissue sample. However, a method for getting the fingerprint to made.

DNA fingerprints and crime
The DNA fingerprint technique Jeffreys plan depends on DNA probes—small fragments of DNA shaped by machines called DNA synthesizers. Each labeled with a radioactive tag. This allows fragment pattern from the samples to see on film and compare.

DNA evidence first case
A 1987 Florida sexual assault case mark the wide taking of DNA evidence in the crime. There have over 20000 cases in which attorneys border control on a human. In addition to there are others who have the chance to use gleaned from DNA testing.

The DNA tests work best when it can argue that a defendant’s DNA does not match the DNA at the crime scene.

In another hand, a defendant can rule out easily as the performer. It is much more difficult to prove that a particular defendant and no other person can possibly commit the crime.

However, it is in criminal trials that the probability of a DNA sample having come from any person other than the defendant so infinitesimally small that a jury is readily sold on the defendant’s guilty.

RFLP

Two processes for DNA fingers prints, both uses of Jeffreys main techniques.The more time-consuming analysis, called (RFLP). It may take weeks to finish. it must base on good DNA. The sample must large by DNA from other organisms. More, extreme conditions can damage DNA and make RFLP analysis fail.

 

 

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